Dan He Lab · School of Chemistry, Chemical Engineering and Biotechnology · NTU Singapore
We build chemical and protein tools to see, record, and reprogram metal chemistry in cells — work anchored in copper, the metal where biology's redox chemistry is most consequential and least understood.
Our ResearchCopper only became available to life after the oceans filled with oxygen, and the enzymes that followed make animals animal — respiration, connective tissue, neurotransmitters. But that redox capacity requires copper to be tightly regulated, by protein networks that control its import, export, and delivery. We want to understand how this metal shaped life, and how to use it to do chemistry that has never happened in nature.
Updates
The He Lab is growing and looking for motivated scientists to join us at the interface of chemistry, biology, and computation. We welcome postdocs, PhD students, and research staff with backgrounds in chemical biology, biochemistry, organic chemistry, or computational biology.
Positions & How to ApplyAcknowledgements